![](https://elearning.usm.my/sidang2324/pluginfile.php/321763/course/overviewfiles/Image.jpg)
This course explains the mechanisms of main reactions in synthesis of small molecules / drugs such as (i) nucleophilic addition reactions of double bonds and conjugated dienes, including Diels-Alder reaction, (ii) nucleophilic addition reactions of carbonyl group, (iii) nucleophilic acyl substitution reactions of carboxylic acids and their derivatives involving synthesis and hydrolysis of esters, lactams, amides, lactones, and sulfonamides; and (iv) substitution reactions of carbonyl compounds at alpha carbon, including enols and enolates concepts, and also carbonyl condensation reactions. This course also learns the theories and applications of spectroscopic methods of UV, IR, NMR and MS, particularly in structural elucidation of simple organic compounds / drugs. Also, understanding the concept pf acid and base of drug such as pH, pKa, buffer solution, drug ionization; and the chemical stability of drug.
- Lecturer: DR. EZATUL EZLEEN BINTI KAMARULZAMAN
- Lecturer: DR. FAUZIAHANIM BINTI ZAKARIA
- Lecturer: DR. ROZA DIANITA
Skill Level: Beginner